Download BEST version 3.0BEST version 3.0 is avaiable at https://github.com/lliu1871/BEST
Download version 2.3.1
(Updated: January 31, 2010)
To download the software you must have a registered and verified email address.
You can register easily here, all you need is an email address. You will receive an email with a link that you must click to validate that address and complete the registration process. Also, indicate below if you would like to receive a notice whenever BEST is updated.
BEST (version 2.3) is the source code for Liang Liu's new algorithm that estimates the posterior joint distribution of Gene trees and the posterior distribution of the species tree jointly in one MCMC algorithm. This code works as a modification of the popular phylogenetics software package MrBayes (Ronquist and Huelsenbeck, Bioinformatics, 2003). BEST parameters are defined using the prset command in MrBayes.
Windows: Executable for the Windows version of BEST estimating posterior distribution of gene trees and species trees jointly.
Mac OS X (Terminal.app): Executable for the Macintosh version of BEST estimating posterior distributions of gene trees and species tree jointly. (Note - users have reported a bug in the executable. After unzipping, double clicking the icon will open your terminal program for command line usage, however the program loses track of the directory it is located in and you must specify full file names, including the directory, for commands such as execute and sumt. To avoid the probelm, open your terminal program first and run the executable from there.)
GUI Betas: Mac and Windows executables with a simple user interface are now available in beta version. Open .txt or .nex files then change or fill-in MrBayes and BEST parameters and run the MCMC and view summaries within the interface.
BEST version 2.2 is also available for use on the BioHPC compute cluster at the Computational Biology Service Unit at Cornell University. Go to http://cbsuapps.tc.cornell.edu/best.aspx to run BEST using this resource.
Please send reports of any bugs in this version or about general issues related to BEST to Liang Liu.
Questions regarding the Macintosh executable or compiling the source code for Macintosh computers (but not about BEST itself) should be sent to Liang Liu.
Questions about using the GUI should be sent to Dennis Pearl.